Wednesday, April 18, 2012

Roundup Herbicide Linked To Parkinson's-Related Brain Damage

Sayer Ji, Contributor
Activist Post

Alarming new research published in the journal Neurotoxicology and Teratology supports the emerging connection between glyphosate, the active ingredient in Roundup herbicide, and neurodegenerative conditions such as Parkinson’s disease and Parkinsonian disorders.

Published this month (April, 2012), the new study entitled "Glyphosate induced cell death through apoptotic and authophagic mechanisms," investigated the potential brain-damaging effects of herbicides, which the authors stated "have been recognized as the main environmental factor associated with neurodegenerative disorders, such as Parkinson’s disease."

They found that glyphosate inhibited the viability of differentiated test cells (PC12, adrenal medula derived), in both dose-and-time dependent manners. The researchers also found that "glyphosate induced cell death via authophagy pathways in addition to activating apoptotic pathways."

Roundup herbicide is now a ubiquitous contaminant in our air, rain, groundwater, and food, making complete avoidance near impossible. A growing body of experimental evidence now indicates that it in addition to its neurotoxicity it also has the following.

Modes of Toxicity
  • Carcinogen
  • Endocrine Disruptor
  • Genotoxic
  • Biocide
  • Cytotoxic
  • Bioaccumulator
  • Hepatotoxic
  • Teratrogenic
  • Clastogenic
  • Oxidant
  • Aquacidal
  • Mutagenic
  • Aromatase Disruptor
  • Glutathione Down-regulator
  • Malondialdehyde Up-regulator
  • Necrotic
  • Nephrotoxic
Once marketed as "safe as table salt" by Monsanto, the original patent holder and manufacturer of this glyphosate-based herbicide, evidence now indicates it is toxic to human DNA at concentrations diluted 450-fold lower than used in agricultural applications.

This study only adds to human case reports of glyphosate-poisoning and/or occupational exposure where neurological damage was a direct consequence. A 2011 case study published in the journal Parkinsonism Related Disorders, entitled "Parkinsonism after chronic occupational exposure to glyphosate," reported the following incident:

Here we report a patient with parkinsonism following chronic occupational exposure to glyphosate. A previously healthy 44- year-old woman presented with rigidity, slowness and resting tremor in all four limbs with no impairment of short-term memory, after sustaining long term chemical exposure to glyphosate for 3 years as a worker in a chemical factory. The chemical plant produced a range of herbicides including: glyphosate, gibberellins, and dimethyl hydrogen phosphite; however, the patient worked exclusively in the glyphosate production division. She only wore basic protection such as gloves or a face mask for 50 h each week in the plant where glyphosate vapor was generated. She frequently felt weak. Two months before she came to our clinic, she had expe- rienced severe dizziness and blurred vision.

Another case study published in 2003 reported a case of parkinsonism subsequent to glyphosate exposure.

These case studies are also backed up by animal research. In the roundworm model of glyphosate exposure the chemical results in neurodegeneration directly associated with damage to the dopamine and GABA producing neurons. In the rat model, glyphosate exposure results in oxidative brain damage, particularly the substantia nigra, where the highest concentration of dopamine-producing cells reside, and which is the primary locus of neurological damage in Parkinson’s disease.

This article first appeared at GreenMedInfo.  Please visit to access their vast database of articles and the latest information in natural health.


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Anonymous said...

I was fishing once by our local resevoir, and about 20 feet or so from the roadside. I heard a large truck coming, slowly, and before I knew what happened, I was apparently deliberately sprayed with Roundup. Some of it got into the lake. I'm sure this was deliberately done, because people of color sometimes fish by this lake, and I have no doubt this was not an accident.

Anonymous said...

Stay healthy my friend,maybe one exposure to herbicide wont harm you,I hope with parkinson is a challenge.

Anonymous said...

A dear friend of mine was diagnosed with Parkinson's ten years ago. His doctor told him point blank it was due to his habitual spraying of Roundup in his yard, so this was known at least ten years ago yet it is still on the market killing people and the planet. It's nothing short of murder.

HealthMinded said...

I have multiple chemical sensitivities and we never know what exposure we have to all the chemicals in our lives all around us every day may affect our health forever. The liver filters toxins and when more toxins are coming in than it can handle, the results can be devastatingly life-altering. Every time someone uses lysol, febreze, air freshener, perfume, cologne, scented deodorant, scented detergent, herbicides, insecticides.....the list goes on and on it, affects our health whether we have symptoms or not. As a matter of fact, many DO have symptoms and they don't realize that is what it is. A headache that comes on all of a sudden, mood swings, stomach distress etc....these can all be symptoms of coming into contact through touch or air with any and all chemicals. I could go on and on, but you get the picture. Thank you for your article and I hope many read it!

Anonymous said...

This is one case in a Chinese factory making many chemicals and with no basis to say it is caused by glyphosate . She was injected with something what does that do. So is the incidence of Parkinson's higher when only glyphosate is present ? This is just hopelessly bad science and worthless to help people assess risk

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