Friday, July 5, 2013

New Study Confirms Wheat-Autism Link

Sayer Ji
Activist Post

As the autism epidemic continues to accelerate, one of the least well known contributing factors goes mostly unnoticed: wheat consumption.

A new study published in the open access journal PLoS is reinvigorating the debate over what are the primary causes of the accelerating autism epidemic. Whereas too many within the conventional medical establishment, failing to identify a singular cause, apathetically label the condition "idiopathic," i.e. cause unknown, or worse, "caused by unknown defective genes," there is a growing awareness that a multitude of environmental factors including vaccines, chemical exposures, C-sections, antibiotics, genetically modified food, and food intolerances are essential in both understanding and treating this disturbing affliction.

The point therefore is not to prove one thing the cause (e.g. "autism genes"), and another not the cause (e.g. vaccines), as if it were strictly some kind of academic sport or past time, rather, to acknowledge possible contributing factors, and eliminate them whenever possible as a precaution.

The new study titled, "Markers of Celiac Disease and Gluten Sensitivity in Children with Autism," explored the possible association between gluten sensitivity and autism, which previous research has confirmed only inconsistently.[i]

They described their aim as follows: "[T]o assess immune reactivity to gluten in pediatric patients diagnosed with autism according to strict criteria and to evaluate the potential link between autism and celiac disease."

They discovered that children with autism had significantly higher levels of IgG antibodies to gliadin, the primary immunotoxic protein in wheat, compared with unhealthy controls. They also found that the IgG anti-gliadin antibody response was significantly greater in the autistic children with gastrointestinal symptoms in comparison to those without them. The elevated IgG antibodies indicate: 1) that their immune systems are identifying gliadin proteins as "other." 2) that gliadin is not being properly broken down through digestive processes and are entering through a compromised intestinal tract ("leaky gut") into the blood.

It has been theorized that when the immune system forms antibodies against gliadin, these antibodies cross react with self-structures within the nervous system. Known as molecular mimicry, this break down of immunological self-tolerance can contribute to wide range of neurological problems including neuropathy, ataxia, seizures, and neurobehavioral changes including mania, schizophrenia and autism. Anti-gliadin antibodies are therefore a possible cause of autoimmune neurological damage. One study published in the Journal of Immunology in 2007 found that anti-gliadin antibodies crossreact with the neurological protein class known as synapsin I, providing a molecular mechanism behind how an immune reaction to gliadin could contribute to neurological degeneration.

Beyond Celiac Disease: Wheat Causes Far More Harm Than Commonly Understood

When the researchers looked at levels of celiac disease specific blood markers (i.e. antibodies to deamidated gliadin and TG2), they did not differ between patients and controls. Moreover, there was no observed association between the HLA-DQ2 genetic locus of celiac disease susceptibility and increased anti-gliadin antibodies. This is an important finding, as many look upon wheat intolerance or sensitivity as a rare disorder without a clearly defined mechanism of action like celiac disease. They would rather not believe that wheat, which is a glorified grain in wealthier countries, could contribute to a wide range of diseases. Our project, for instance, has identified over 200 potential adverse health effects of gluten consumption. One does not therefore have to have classically defined celiac disease, or "wheat allergy," to experience adverse effects associated with gluten-grain consumption.

The authors of the study concluded:
A subset of children with autism displays increased immune reactivity to gluten, the mechanism of which appears to be distinct from that in celiac disease. The increased anti-gliadin antibody response and its association with GI symptoms points to a potential mechanism involving immunologic and/or intestinal permeability abnormalities in affected children.
Scientists are cautious, and they should be. For those who are suffering with an autistic child or family member, however, a gluten free diet might be worth exploring now, even if the link is only considered tentative from the perspective of the peer-reviewed clinical literature. One remarkable example of the potential for a gluten free diet to generate great improvement can be viewed on Recovers from Autism After Going Gluten Free.

Interesting in learning more about this topic? Read:

Wheat: A Missing Piece in the Autism Puzzle

From Autism to Anorexia, It's All About the Gut

The Dark Side of Wheat

[i] Nga M Lau, Peter H R Green, Annette K Taylor, Dan Hellberg, Mary Ajamian, Caroline Z Tan, Barry E Kosofsky, Joseph J Higgins, Anjali M Rajadhyaksha, Armin Alaedini. Markers of Celiac Disease and Gluten Sensitivity in Children with Autism. PLoS One. 2013 ;8(6):e66155. Epub 2013 Jun 18. PMID:23823064

This article first appeared at GreenMedInfo.  Please visit to access their vast database of articles and the latest information in natural health.


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Anonymous said...

Right. Sure. It's not the toxic vaccines and GMO food.
It's natural grain whole wheat.

I guess it's true you can't fix stupid.
and anyone buying this is just that...Stupid!

Anonymous said...

The authors of the study concluded:

"With the amount of the check they were receiving from Big Pharma certainly a subset of children with autism display increased immune reactivity to gluten, the mechanism of which appears to be distinct from that in celiac disease. It stands to reason that the string of zeros behind that large first number dictates this is the case. The increased anti-gliadin antibody response and its association with GI symptoms points to a potential mechanism involving immunologic and/or intestinal permeability abnormalities in affected children with parents stupid enough to fall for this BS."

Anonymous said...

Now here's a thought: What if the vaccines were causing this genetic anomaly thus causing the body to react to wheat as it does in these kids?

Anonymous said...

The wheat we eat today, is NOT the wheat that was first sown and grown when humanity first understood growing food from seeds.

It has been altered and manipulated to provide more profit, and consequently infiltrated with a high number of invasive chemical substances, which are then ingested by consumers.

The same can be said for all major food groups, except of course, for organic food, which, quite naturally, is very expensive!!

Anonymous said...

Those are NOT Olive branches on the UN Symbol. It goes that deep....

Dr Bonnie said...

Dr Bernard Rimland's research showed that 66% of autistic children improved on a gluten and dairy-free diet. This does not preclude the fact that vaccinations and other sources of heavy metals like mercury and aluminum are also contributing factors to many cases of autism.

somitcw said...

The wheat that we eat is not natural domesticated wheat. About two hundred years ago, wheat was breed to be insect resistant. The result was wheat that if eaten by insects would destroy the gut of those insects. Well, guess what, it doesn't seem to be too healthy for some human guts either.
A 2010 German study showed that children that receive vaccines have two to five times as much disease as vaccinated children. The worst ones were diseases like asthma, allergies, and autism. Perhaps vaccines have an impact on children's immune systems? Duh.
In 1999, a study showed that newborns that received the hepatitis vaccine had a triple rate of autism. We then changed the poison mercury in vaccines to poison aluminum.
Yes, autism has an intestinal component but breeding all wheat to destroy insect guts is not the only cause.

Anonymous said...

Then there's the Amish who feed their children lot's of wheat products and never allow any vaccines or GMO food and they never seem to have any Autism in their children.
Just a coincidence I'm sure an anomaly that has no bearing on the new facts that wheat causes Autism not Vaccines.

Anonymous said...

We know GMOs are engineered to explode the stomach's of insects & they're doing the same thing to people, except in the intestines which cause leaky gut & that obviously releases bacteria into the bloodstream affecting brain function etc. GMO's are protected bio-warfare on our food supply & Citizenry.

Anonymous said...

then, should we avoid eating wheat? or what should we do?

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